The 2005 Major League Baseball season was notable for the league's new steroid policy in the wake of the BALCO scandal, which enforced harsher penalties ever than before for steroid use in Major League Baseball. Several players, including veteran Rafael Palmeiro, were suspended under the new policy. Also, every team in the NL East division had at least 81 wins (at least half of the 162 games played). It was also notable for being the first season featuring a baseball team in Washington, DC for more than 4 decades, with the Washington Nationals having moved from Montreal.
The season ended when the Chicago White Sox defeated the Houston Astros in a four-game sweep in the World Series, winning their first championship since 1917. Taken from https://en.wikipedia.org/wiki/2005_Major_League_Baseball_season

Final Stats:

MLB Detailed Standings
Tm	Lg	G	W	L	W-L% ▾
STL	NL	162	100	62	0.617
CHW	AL	162	99	63	0.611
BOS	AL	162	95	67	0.586
NYY	AL	162	95	67	0.586
LAA	AL	162	95	67	0.586
CLE	AL	162	93	69	0.574
ATL	NL	162	90	72	0.556
HOU	NL	163	89	73	0.549
PHI	NL	162	88	74	0.543
OAK	AL	162	88	74	0.543
NYM	NL	162	83	79	0.512
FLA	NL	162	83	79	0.512
MIN	AL	162	83	79	0.512
SDP	NL	162	82	80	0.506
MIL	NL	162	81	81	0.5
WSN	NL	162	81	81	0.5
TOR	AL	162	80	82	0.494
TEX	AL	162	79	83	0.488
CHC	NL	162	79	83	0.488
ARI	NL	162	77	85	0.475
SFG	NL	162	75	87	0.463
BAL	AL	162	74	88	0.457
CIN	NL	163	73	89	0.451
DET	AL	162	71	91	0.438
LAD	NL	162	71	91	0.438
SEA	AL	162	69	93	0.426
TBD	AL	162	67	95	0.414
COL	NL	162	67	95	0.414
PIT	NL	162	67	95	0.414
KCR	AL	162	56	106	0.346
Postseason
WorldSeries (4-0):	Chicago White Sox over Houston Astros
ALCS (4-1):	Chicago White Sox over Los Angeles Angels of Anaheim
NLCS (4-2):	Houston Astros over St. Louis Cardinals
LDS (3-0):	Chicago White Sox over Boston Red Sox
LDS (3-2):	Los Angeles Angels of Anaheim over New York Yankees
LDS (3-0):	St. Louis Cardinals over San Diego Padres
LDS (3-1):	Houston Astros over Atlanta Braves
Most runs per game: 5.6
Boston Red Sox
Fewest runs allowed per game: 3.7
Houston Astros
Chicago White Sox Stats:
Most runs in a game: 15
Wednesday, Jun 8	boxscore	CHW	@	COL	W	15	5
Longest game by time: 5:09
Tuesday, Aug 16	boxscore	CHW		MIN	L	4	9	16 innings